Prabhu Balan

Citation

Thesis Title
Effects of orally administered ovine serum immunoglobulin in the normal and Salmonella enteritidis-challenged growing rats

Read article at Massey Research Online:

Immunoglobulins (lgs), proteins synthesised by animals, are the first line of defence against invading pathogens. They can be extracted from animal blood and used prophylactically and therapeutically. Mr Balan, using physiological, immunological, molecular and microbiological techniques, has shown that feeding an ovine Ig fraction enhances growth performance, modulates various indices of immune function, increases the numbers of beneficial lactobacilli in the gut and also influences gut mucin content in the normal and Salmonella enteritidis - challenged rat. He has also found that intact ovine Ig can be detected in the luminal contents of the digestive tract of growing rats given an ovine Ig fraction orally. The results contribute to knowledge of how ovine Igs can modulate and enhance key indicators of gut function, immunity and overall growth performance in mammals.

Supervisors
Distinguished Professor Paul Moughan
Distinguished Professor Harjinder Singh
Dr Kyoung Han