Ignacio Lizarraga-Madrigal

Citation

Thesis Title
Spinal analgesic interaction between non-steroidal anti-inflammatory drugs and N-methyl D-aspartate receptor systems.

Read article at Massey Research Online:

Dr Lizarraga-Madrigal studied the potential analgesic interactions between aspirin-like drugs and NMDA receptor systems at the spinal cord level. He carried out a series of studies. The studies’ objectives involved identifying drug combinations that would control pain in a more efficient way and produce less side effects compared to individual drugs. Using electrophysiological and behavioural techniques, his research showed that combinations of ketoprofen, ketamine and L-NAME may be useful for controlling pain and producing less side effects compared to using each individual drug. These findings may be of clinical relevance for both animals and humans

Supervisors
Professor Craig Johnson