Contact details +6469517648

Dr Patrick Edwards PhD

Senior Research Officer in Chemistry

Doctoral Supervisor
School of Food Technology and Natural Sciences

I manage the Massey bioNMR facility.  My area of expertise is the application of Nuclear Magnetic Resonance (NMR) spectroscopy to chemical and biological problems. These include the study of protein, carbohydrate and RNA/DNA structure and dynamics as well as the structure determination of small organic molecules. I have experience with NMR-based metabolomics, which we can offer as a service, using our 700 MHz spectrometer (the most powerful in NZ). I also use NMR to study molecules and (liquid crystal) molecular systems under non quiescent conditions such as high pressure and under shear (rheo-NMR).

Professional

Contact details

  • Ph: 84648
    Location: ScC 1.04 (Bio-NMR Lab), Science Tower C
    Campus: Turitea

Qualifications

  • Doctor of Philosophy - University of Leeds (1993)

Certifications and Registrations

  • Licence, Supervisor, Massey University

Research Expertise

Research Interests

My area of expertise is the application of Nuclear Magnetic Resonance (NMR) spectroscopy to chemical problems.  These include the study of protein structure and dynamics and the structure determination of small organic molecules. I also use NMR to study molecules and (liquid crystal) molecular systems under non quiescent conditions such as high pressure and under shear (rheo-NMR).  I have an emerging interest in NMR based metabolomics.  As Manager of the BioNMR facility, I am responsible for keeping the highly sophisticated equipment running to specification, and for training students and others in its use.

 

Thematics

21st Century Citizenship, Resource Development and Management, Design – for Commerce, Community and Culture, Health and Well-being, Future Food Systems

Area of Expertise

Field of research codes
Analytical Chemistry (030100): Analytical Spectrometry (030101):
Biochemistry and Cell Biology (060100): Biological Sciences (060000):
Chemical Science (030000): Instrumental Methods (excl. Immunological and Bioassay Methods) (030105): Physical Chemistry (incl. Structural (030600):
Structural Biology (incl. Macromolecular Modelling) (060112):
Structural Chemistry and Spectroscopy (030606):
Systems Biology (060114)

Keywords

NMR, Nuclear Magnetic Resonance, Metabolomics, Structural biology, Rheo-NMR, High Pressure NMR.

Research Projects

Summary of Research Projects

Position Current Completed
Project Leader 0 4
Team Member 0 2

Completed Projects

Project Title: NMR Spectroscopy Based Metabolic Profiling

Date Range: 2013 - 2013

Funding Body: Massey University

Project Team:

Project Title: New NMR Technologies and Products

Date Range: 2012 - 2015

Funding Body: Research Trust of Victoria University of Wellington, The

Project Team:

Project Title: Muscle damage and Metabolomics

Date Range: 2010 - 2011

Funding Body: Massey University

Project Team:

  • Prof Steve Stannard - Project Leader
  • Dr Patrick Edwards - Team Member
  • Prof Julian Heyes - Team Member

Project Title: Optimal chemical and physical conditions for the origin of RNA life forms

What are the environmental, chemical and physical requirements for the evolution of stable, selfreplicating, chemical systems of increasing complexity, that is, of life? There is now a general acceptance that RNA preceded DNA and encoded proteins in the origin of life, performing the functions of both. That is, RNA molecules stored genetic information and functioned as catalysts (ribozymes). There has been much interest in the possibility that life began at high temperatures near chemically and energy rich 'black smokers'. However, this poses problems for RNA-based life forms, as at high temperatures and low pressures RNA is known to unfold and decompose. In this project we aim to provide the first chemical and physical studies examining the role of both pressure and temperature on chemical and physical stability of RNA and its constituents to answer the fundamental question: Can high pressure and the molecular crowding of cellular soups offset the destabilising effects of high temperature on RNA and its constituent nucleotides?
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Date Range: 2010 - 2013

Funding Body: Marsden Fund - Full

Project Team:

Research Outputs

Journal

Garavís, M., Edwards, PJB., Serrano-Chacón, I., Doluca, O., Filichev, VV., & González, C. (2024). Understanding int er calativ e modulation of G-ric h sequence folding: solution structure of a TINA-conjugated antiparallel DNA triplex. Nucleic Acids Research. 52(5), 2686-2697
[Journal article]Authored by: Edwards, P., Filichev, V.
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Bisht, A., Goh, KKT., Sims, IM., Edwards, PJB., & Matia-Merino, L. (2024). Does harvesting age matter? Changes in structure and rheology of a shear-thickening polysaccharide from Cyathea medullaris as a function of age. Carbohydrate Polymers. 329
[Journal article]Authored by: Edwards, P., Goh, K., Matia-Merino, M.
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Sajjad, MA., Schwerdtfeger, P., Edwards, PJB., Harrison, JA., & Nielson, AJ. (2023). Chasing the CMD/AMLA Mechanism C-H···Pd Interactions in the Cyclopalladation Reaction of N,N-Dimethylbenzylamine with Pd(OAc)<inf>2</inf>. Organometallics. 42(23), 3343-3356
[Journal article]Authored by: Edwards, P., Schwerdtfeger, P.
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1
Bisht, A., Goh, KKT., Sims, IM., Edwards, PJB., & Matia-Merino, L. (2023). Shear and temperature sensitivity of a shear-thickening biopolymer from the New Zealand black tree fern. Food Hydrocolloids. 145
[Journal article]Authored by: Edwards, P., Goh, K., Matia-Merino, M.
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3
Harjes, E., Edwards, PJB., Bisset, SW., Patchett, ML., Jameson, GB., Yang, SH., . . . Norris, GE. (2023). NMR Shows Why a Small Chemical Change Almost Abolishes the Antimicrobial Activity of Glycocin F. Biochemistry. 62(17), 2669-2676
[Journal article]Authored by: Edwards, P., Jameson, G.
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Mohandas, N., Edwards, PJB., Kent, LM., Jameson, GB., & Williams, MAK. (2023). Biotinylation of reducing and non-reducing termini to create plug-and-play polysaccharides. Carbohydrate Polymers. 305
[Journal article]Authored by: Edwards, P., Jameson, G.
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2
Ang, CL., Matia-Merino, L., Sims, IM., Sargison, L., Edwards, PJB., Lim, K., . . . Goh, KKT. (2022). Characterisation of de-structured starch and its shear-thickening mechanism. Food Hydrocolloids. 132
[Journal article]Authored by: Edwards, P., Goh, K., Matia-Merino, M.
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3
Montoya, CA., Henare, SJ., O'Donoghue, EM., Rosendale, D., Edwards, P., & Moughan, PJ. (2021). Kiwifruit (: Actinidia deliciosa), compared with cellulose and psyllium, influences the histology and mucus layer of the gastrointestinal tract in the growing pig. Food and Function. 12(17), 8007-8016
[Journal article]Authored by: Edwards, P., Henare, S.
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3
Varnava, KG., Edwards, PJB., Cameron, AJ., Harjes, E., & Sarojini, V. (2021). Cyclic peptides bearing the d-Phe-2-Abz turn motif: Structural characterization and antimicrobial potential. Journal of Peptide Science. 27(2)
[Journal article]Authored by: Edwards, P.
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4
Harjes, E., Jameson, GB., Tu, YH., Burr, N., Loo, TS., Goroncy, AK., . . . Norris, GE. (2021). Experimentally based structural model of Yih1 provides insight into its function in controlling the key translational regulator Gcn2. FEBS Letters. 595(3), 324-340
[Journal article]Authored by: Edwards, P., Harjes, S., Jameson, G., Loo, T., Sattlegger, E.
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1
Samuelsson, LM., Olivecrona, N., Cônsolo, NNB., Reis, MM., Reis, MG., & Edwards, PJB. (2021). Preparation of drip samples from leg of lamb with extended shelf life for nuclear magnetic resonance metabolomics studies. Meat Science. 172
[Journal article]Authored by: Edwards, P.
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6
Cônsolo, NRB., Olivecrona, N., Samuelsson, LM., Reis, MG., Edwards, PJB., & Reis, MM. (2020). Investigation of metabolites associated with confinement odour in chilled vacuum-packed lamb by proton nuclear magnetic resonance (<sup>1</sup>H NMR) spectroscopy. Meat Science. 169
[Journal article]Authored by: Edwards, P.
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5
Su, Y., Edwards, PJB., Stetsenko, DA., & Filichev, VV. (2020). The Importance of Phosphates for DNA G-Quadruplex Formation: Evaluation of Zwitterionic G-Rich Oligodeoxynucleotides. ChemBioChem. 21(17), 2455-2466
[Journal article]Authored by: Edwards, P., Filichev, V.
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2
Leung, YB., Cave, NJ., Heiser, A., Edwards, PJB., Godfrey, AJR., & Wester, T. (2020). Metabolic and Immunological Effects of Intermittent Fasting on a Ketogenic Diet Containing Medium-Chain Triglycerides in Healthy Dogs. Frontiers in Veterinary Science. 6
[Journal article]Authored by: Edwards, P., Godfrey, A., Wester, T.
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2
Lepper, CP., Williams, MAK., Edwards, PJB., Filichev, VV., & Jameson, GB. (2019). Effects of Pressure and pH on the Physical Stability of an I-Motif DNA Structure. ChemPhysChem. 20(12), 1567-1571
[Journal article]Authored by: Edwards, P., Filichev, V., Jameson, G.
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Filitcheva, J., Edwards, PJB., Norris, GE., & Filichev, VV. (2019). α-2′-Deoxyguanosine can switch DNA G-quadruplex topologies from antiparallel to parallel. Organic and Biomolecular Chemistry. 17(16), 4031-4042
[Journal article]Authored by: Edwards, P., Filichev, V.
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Naffa, R., Edwards, PJB., & Norris, G. (2019). Isolation and characterization of collagen type I crosslink from skin: high-resolution NMR reveals diastereomers of hydroxylysinonorleucine crosslink. Amino Acids. 51(4), 705-715
[Journal article]Authored by: Edwards, P.
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7
Cameron, AJ., Varnava, KG., Edwards, PJB., Harjes, E., & Sarojini, V. (2018). Acyclic peptides incorporating the d-Phe-2-Abz turn motif: Investigations on antimicrobial activity and propensity to adopt β-hairpin conformations. Journal of Peptide Science. 24(8-9)
[Journal article]Authored by: Edwards, P.
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4
Matthews, ZM., Collett, MG., Marshall, JC., Partridge, AC., Derrick, PJ., & Edwards, PJB. (2018). Effect of a one-off sporidesmin challenge on the milk production of dairy cows. New Zealand Veterinary Journal. 66(5), 261-266
[Journal article]Authored by: Edwards, P., Marshall, J.
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Matthews, ZM., Edwards, PJB., Kahnt, A., Collett, MG., Marshall, JC., Partridge, AC., . . . Derrick, PJ. (2018). Serum metabolomics using ultra performance liquid chromatography coupled to mass spectrometry in lactating dairy cows following a single dose of sporidesmin. Metabolomics. 14(5)
[Journal article]Authored by: Edwards, P., Marshall, J.
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3
Lepper, CP., Williams, MAK., Penny, D., Edwards, PJB., & Jameson, GB. (2018). Effects of Pressure and pH on the Hydrolysis of Cytosine: Implications for Nucleotide Stability around Deep-Sea Black Smokers. ChemBioChem. 19(6), 540-544
[Journal article]Authored by: Edwards, P., Jameson, G.
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Mittal, VA., Ellis, A., Ye, A., Edwards, PJB., & Singh, H. (2018). The adsorption of orthophosphate onto casein-iron precipitates. Food Chemistry. 239, 17-22
[Journal article]Authored by: Edwards, P., Singh, H., Ye, A.
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Cameron, AJ., Edwards, PJB., Harjes, E., & Sarojini, V. (2017). Tyrocidine A Analogues Bearing the Planar d-Phe-2-Abz Turn Motif: How Conformation Impacts Bioactivity. Journal of Medicinal Chemistry. 60(23), 9565-9574
[Journal article]Authored by: Edwards, P.
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Cameron, AJ., Squire, CJ., Edwards, PJB., Harjes, E., & Sarojini, V. (2017). Crystal and NMR Structures of a Peptidomimetic β-Turn That Provides Facile Synthesis of 13-Membered Cyclic Tetrapeptides. Chemistry - An Asian Journal. 12(24), 3195-3202
[Journal article]Authored by: Edwards, P.
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Lam, E., Holt, C., Edwards, P., McKinnon, I., Otter, D., Li, N., . . . Hemar, Y. (2017). The effect of transglutaminase treatment on the physico-chemical properties of skim milk with added ethylenediaminetetraacetic acid. Food Hydrocolloids. 69, 329-340
[Journal article]Authored by: Edwards, P.
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Harjes, S., Jameson, GB., Filichev, VV., Edwards, PJB., & Harjes, E. (2017). NMR-based method of small changes reveals how DNA mutator APOBEC3A interacts with its single-stranded DNA substrate. Nucleic Acids Research. 45(9), 5602-5613
[Journal article]Authored by: Edwards, P., Filichev, V., Harjes, S., Jameson, G.
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Lepper, CP., Williams, MAK., & Edwards, PJB. (2016). On the properties of residual dipolar coupling alignment tensors: Simulations illuminate how residual dipolar couplings depend on the relative orientations of the magnetic field, the director of the alignment phase and the bond vectors. Concepts in Magnetic Resonance Part A: Bridging Education and Research. 45A(5)
[Journal article]Authored by: Edwards, P.
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Mittal, VA., Ellis, A., Ye, A., Edwards, PJB., Das, S., & Singh, H. (2016). Iron binding to caseins in the presence of orthophosphate. Food Chemistry. 190, 128-134
[Journal article]Authored by: Edwards, P., Singh, H., Ye, A.
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Doluca, O., Withers, JM., Loo, TS., Edwards, PJB., González, C., & Filichev, VV. (2015). Interdependence of pyrene interactions and tetramolecular G4-DNA assembly. Organic and Biomolecular Chemistry. 13(12), 3742-3748
[Journal article]Authored by: Edwards, P., Filichev, V., Loo, T.
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15
Ren, L., Edwards, PJB., Perera, CO., & Hemar, Y. (2015). Structural features of a novel polysaccharide isolated from a New Zealand Maori mushroom Iliodiction cibarium. Carbohydrate Research. 406, 19-26
[Journal article]Authored by: Edwards, P.
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Brimble, MA., Edwards, PJ., Harris, PWR., Norris, GE., Patchett, ML., Wright, TH., . . . Carley, SE. (2015). Synthesis of the antimicrobial S-linked glycopeptide, glycocin F. Chemistry (Weinheim an der Bergstrasse, Germany). 21(9), 3556-3561
[Journal article]Authored by: Edwards, P.
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Doluca, O., Hale, TK., Edwards, PJB., González, C., & Filichev, VV. (2014). Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence-Specific Detection of Double-Stranded DNA.. Chempluschem. 79(1), 2
[Journal article]Authored by: Edwards, P., Filichev, V., Hale, T.
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Lepper, CP., Williams, MAK., Edwards, PJ., & Jameson, GB. (2014). The effects of high pressure and pH on the hydrolysis of cytosine at high temperature. Chemistry in New Zealand. 78(3), 122-125 Retrieved from https://nzic.org.nz/
[Journal article]Authored by: Edwards, P., Jameson, G.
Pinu, FR., Edwards, PJB., Gardner, RC., & Villas-Boas, SG. (2014). Nitrogen and carbon assimilation by Saccharomyces cerevisiae during Sauvignon blanc juice fermentation. FEMS Yeast Research. 14(8), 1206-1222
[Journal article]Authored by: Edwards, P.
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Suzuki, R., Irie, R., Harntaweesup, Y., Tachibana, K., Holland, PT., Harwood, DT., . . . Satake, M. (2014). Brevisulcatic acids, marine ladder-frame polyethers from the red tide dinoflagellate Karenia brevisulcata in New Zealand. Organic Letters. 16(22), 5850-5853
[Journal article]Authored by: Edwards, P.
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Pinu, FR., Edwards, PJB., Jouanneau, S., Kilmartin, PA., Gardner, RC., & Villas-Boas, SG. (2014). Sauvignon blanc metabolomics: Grape juice metabolites affecting the development of varietal thiols and other aroma compounds in wines. Metabolomics. 10(4), 556-573
[Journal article]Authored by: Edwards, P.
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Doluca, O., Hale, TK., Edwards, PJB., Gonzalez, C., & Filichev, VV. (2014). Assembly dependent fluorescence enhancing nucleic acids in sequence-specific detection of double-stranded DNA. ChemPlusChem. 79(1), 58-66
[Journal article]Authored by: Edwards, P., Filichev, V., Hale, T.
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Pinu, FR., Edwards, PJB., Jouanneau, S., Kilmartin, PA., Gardner, RC., & Villas-Boas, SG. (2013). Sauvignon blanc metabolomics: grape juice metabolites affecting the development of varietal thiols and other aroma compounds in wines. Metabolomics. , 1-18
[Journal article]Authored by: Edwards, P.
Ainscough, EW., Brodie, AM., Edwards, PJB., Jameson, GB., Otter, CA., & Kirk, S. (2012). Zinc, cadmium, and mercury complexes of a pyridyloxy-substituted cyclotriphosphazene: Syntheses, structures, and fluxional behavior. Inorganic Chemistry. 51(20), 10884-10892
[Journal article]Authored by: Edwards, P., Jameson, G.
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Hindmarsh, JP., Awati, A., Edwards, PJB., & Moughan, P. (2012). NMR-based metabonomics detection of differences in the metabolism of hydrolysed versus intact protein of similar amino acid profile. Journal of the Science of Food and Agriculture. 92(9), 2013-2016
[Journal article]Authored by: Edwards, P., Hindmarsh, J.
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8
Hindmarsh, JP., Awati, A., Edwards, PJ., & Moughan, P. (2012). NMR-based metabonomics detection of differences in the metabolism of hydrolysed versus intact protein of similar amino acid profile. Journal of the Science of Food and Agriculture.
[Journal article]Authored by: Edwards, P., Hindmarsh, J.
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Holland, PT., Shi, F., Satake, M., Hamamoto, Y., Ito, E., Beuzenberg, V., . . . Pascal, SM. (2012). Novel toxins produced by the dinoflagellate Karenia brevisulcata. Harmful Algae. 13, 47-57
[Journal article]Authored by: Edwards, P., Truman, P.
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Ye, A., Edwards, PJB., Gilliland, J., Jameson, GB., & Singh, H. (2012). Temperature-dependent complexation between sodium caseinate and gum arabic. Food Hydrocolloids. 26(1), 82-88
[Journal article]Authored by: Edwards, P., Jameson, G., Singh, H., Ye, A.
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Lepper, C., Edwards, PJB., Dykstra, R., & Williams, MAK. (2011). Rheo-NMR studies of a nematic worm-like micelle system in a high-shear-rate regime. Soft Matter. 7(21), 10291-10298
[Journal article]Authored by: Edwards, P.
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Lepper, C., Edwards, PJB., Dykstra, R., & Williams, MAK. (2011). Rheo-NMR studies of a nematic worm-like micelle system in a high-shear-rate regime. SOFT MATTER. 7(21), 10291-10298
[Journal article]Authored by: Edwards, P.
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3
Venugopal, H., Edwards, PJB., Schwalbe, M., Claridge, JK., Libich, DS., Stepper, J., . . . Pascal, SM. (2011). Structural, dynamic, and chemical characterization of a novel S-glycosylated bacteriocin. Biochemistry. 50(14), 2748-2755
[Journal article]Authored by: Edwards, P., Loo, T.
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Lepper, C., Edwards, PJB., Schuster, E., Brown, JR., Dykstra, R., Callaghan, PT., . . . Williams, MAK. (2010). Rheo-NMR studies of the behavior of a nematic liquid crystal in a low-shear-rate regime: the transition from director alignment to reorientation.. Phys Rev E Stat Nonlin Soft Matter Phys. 82(4 Pt 1), 041712
[Journal article]Authored by: Edwards, P.
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Lepper, C., Edwards, PJB., Schuster, E., Brown, JR., Dykstra, R., Callaghan, PT., . . . Williams, MAK. (2010). Rheo-NMR studies of the behavior of a nematic liquid crystal in a low-shear-rate regime: The transition from director alignment to reorientation. Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 82(4)
[Journal article]Authored by: Edwards, P.
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Headey, SJ., MacAskill, UK., Wright, MA., Claridge, JK., Edwards, PJB., Farley, PC., . . . Pascal, SM. (2010). Solution structure of the squash aspartic acid proteinase inhibitor (SQAPI) and mutational analysis of pepsin inhibition. Journal of Biological Chemistry. 285(35), 27019-27025
[Journal article]Authored by: Edwards, P.
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Edwards, PJB., Kakubayashi, M., Dykstra, R., Pascals, SM., & Williams, MAK. (2010). Rheo-NMR studies of an enzymatic reaction: Evidence of a shear-stable macromolecular system. Biophysical Journal. 98(9), 1986-1994
[Journal article]Authored by: Edwards, P.
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Schwalbe, M., Dutta, K., Libich, DS., Venugopal, H., Claridge, JK., Gell, DA., . . . Pascal, SM. (2010). Two-state conformational equilibrium in the Par-4 leucine zipper domain. Proteins: Structure, Function and Bioinformatics. 78(11), 2433-2449
[Journal article]Authored by: Edwards, P.
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Ponniah, K., Loo, TS., Edwards, PJB., Pascal, SM., Jameson, GB., & Norris, GE. (2010). The production of soluble and correctly folded recombinant bovine β-lactoglobulin variants A and B in Escherichia coli for NMR studies. Protein Expression and Purification. 70(2), 283-289
[Journal article]Authored by: Edwards, P., Jameson, G., Loo, T.
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Sun, X., Jones, WT., Harvey, D., Edwards, PJB., Pascal, SM., Kirk, C., . . . Uversky, VN. (2010). N-terminal domains of DELLA proteins are intrinsically unstructured in the absence of interaction with GID1/gibberellic acid receptors. Journal of Biological Chemistry. 285(15), 11557-11571
[Journal article]Authored by: Edwards, P., Rakonjac, J.
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Claridge, JK., Headey, SJ., Chow, JYH., Schwalbe, M., Edwards, PJ., Jeffries, CM., . . . Pascal, SM. (2009). Corrigendum to "A picornaviral loop-to-loop replication complex" [J. Struct. Biol. 166 (2009) 251-262] (DOI:10.1016/j.jsb.2009.02.010). Journal of Structural Biology. 168(2), 357
[Journal article]Authored by: Edwards, P.
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Comeskey, DJ., Montefiori, M., Edwards, PJB., & McGhie, TK. (2009). Isolation and structural identification of the anthocyanin components of red kiwifruit. Journal of Agricultural and Food Chemistry. 57(5), 2035-2039
[Journal article]Authored by: Edwards, P.
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Claridge, JK., Headey, SJ., Chow, JYH., Schwalbe, M., Edwards, PJ., Jeffries, CM., . . . Pascal, SM. (2009). A picornaviral loop-to-loop replication complex (vol 166, pg 251, 2009). JOURNAL OF STRUCTURAL BIOLOGY. 168(2), 357-357
[Journal article]Authored by: Edwards, P.
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Libich, DS., Schwalbe, M., Kate, S., Venugopal, H., Claridge, JK., Edwards, PJB., . . . Pascal, SM. (2009). Intrinsic disorder and coiled-coil formation in prostate apoptosis response factor 4. FEBS Journal. 276(14), 3710-3728
[Journal article]Authored by: Edwards, P.
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Libich, DS., Schwalbe, M., Kate, S., Venugopal, H., Claridge, JK., Edwards, PJB., . . . Pascal, SM. (2009). Intrinsic disorder and coiled-coil formation in prostate apoptosis response factor 4.. The FEBS journal. 276(14), 3710-3728
[Journal article]Authored by: Edwards, P.
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Claridge, JK., Headey, SJ., Chow, JYH., Schwalbe, M., Edwards, PJ., Jeffries, CM., . . . Pascal, SM. (2009). A picornaviral loop-to-loop replication complex. Journal of Structural Biology. 166(3), 251-262
[Journal article]Authored by: Edwards, P.
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Koulman, A., Seeliger, C., Edwards, PJB., Fraser, K., Simpson, W., Johnson, L., . . . Lane, GA. (2008). E/Z-Thesinine-O-4′-α-rhamnoside, pyrrolizidine conjugates produced by grasses (Poaceae). Phytochemistry. 69(9), 1927-1932
[Journal article]Authored by: Edwards, P.
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Spencer, P., Sivakumaran, S., Fraser, K., Foo, LY., Lane, GA., Edwards, PJB., . . . Meagher, LP. (2007). Isolation and characterisation of procyanidins from Rumex obtusifolius. Phytochemical Analysis. 18(3), 193-203
[Journal article]Authored by: Edwards, P.
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McGhie, TK., Rowan, DR., & Edwards, PJ. (2006). Structural identification of two major anthocyanin components of boysenberry by NMR spectroscopy. Journal of Agricultural and Food Chemistry. 54(23), 8756-8761
[Journal article]Authored by: Edwards, P.
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Taylor, CM., Hardré, R., & Edwards, PJB. (2005). The impact of pyrrolidine hydroxylation on the conformation of proline-containing peptides. Journal of Organic Chemistry. 70(4), 1306-1315
[Journal article]Authored by: Edwards, P.
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Hudson, DA., Sciascia, QL., Sanders, R., Norris, GE., Edwards, PJ., Sullivan, PA., . . . Farley, PC. (2004). Identification of the dialysable serum inducer of germ-tube formation in candida albicans. Microbiology. 150(9), 3041-3049
[Journal article]Authored by: Edwards, P.
Hudson, DA., Sciascia, QL., Sanders, RJ., Norris, GE., Edwards, PJB., Sullivan, PA., . . . Farley, PC. (2004). Identification of the dialysable serum inducer of germ-tube formation in Candida albicans. Microbiology. 150(9), 3041-3049
[Journal article]Authored by: Edwards, P.
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Taylor, CM., Hardre, R., Edwards, PJ., & Park, JH. (2003). Factors affecting conformation in proline-containing peptides. Organic Letters. 5(23), 4413-4416
[Journal article]Authored by: Edwards, P.
Taylor, CM., Hardré, R., Edwards, PJB., & Park, JH. (2003). Factors Affecting Conformation in Proline-Containing Peptides. Organic Letters. 5(23), 4413-4416
[Journal article]Authored by: Edwards, P.
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Sawyer, L., Barlow, PN., Boland, MJ., Creamer, LK., Denton, H., Edwards, PJB., . . . Norris, GE. (2002). Milk protein structure--what can it tell the dairy industry? [Erratum: 2002, v. 12 (8), p. 709.]. International Dairy Journal.. 12(4), 299-310
[Journal article]Authored by: Boland, M., Edwards, P., Jameson, G.
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Sawyer, L., Barlow, PN., Boland, MJ., Creamer, LK., Denton, H., Edwards, PJB., . . . Wu, SY. (2002). Erratum: Milk protein structure - What can it tell the dairy industry? (International Dairy Journal (2002) 12:4 (299-310) PII: S0958694602000250). International Dairy Journal. 12(8), 709
[Journal article]Authored by: Boland, M., Edwards, P., Jameson, G.
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Smith, MH., Edwards, PJ., Palmano, KP., & Creamer, LK. (2002). Structural features of bovine caseinmacropeptide A and B by ¹H nuclear magnetic resonance spectroscopy. Journal of Dairy Research. 69(1), 85-94
[Journal article]Authored by: Edwards, P.
Sawyer, L., Barlow, PN., Boland, MJ., Creamer, LK., Denton, H., Edwards, PJB., . . . Wu, SY. (2002). Milk protein structure - What can it tell the dairy industry?. International Dairy Journal. 12(4), 299-310
[Journal article]Authored by: Boland, M., Edwards, P., Jameson, G.
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23
Edwards, PJB., Jameson, GB., Palmano, KP., & Creamer, LK. (2002). Heat-resistant structural features of bovine β-lactoglobulin A revealed by NMR H/D exchange observations. International Dairy Journal. 12(4), 331-344
[Journal article]Authored by: Edwards, P., Jameson, G.
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23
Smith, MH., Edwards, PJB., Palmano, KP., & Creamer, LK. (2002). Structural features of bovine caseinomacropeptide A and B by <sup>1</sup>H nuclear magnetic resonance spectroscopy. Journal of Dairy Research. 69(1), 85-94
[Journal article]Authored by: Edwards, P.
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18
Edwards, PJB., Jolley, KW., Smith, MH., Thomsen, SJ., & Boden, N. (1997). Solvent isotope effect on the self-assembly and liquid crystalline phase behavior in aqueous solutions of ammonium pentadecafluorooctanoate. Langmuir. 13(10), 2665-2669
[Journal article]Authored by: Edwards, P.
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Dombroski, JP., Edwards, PJB., Jolley, KW., & Bodenij, N. (1995). Phase diagram of the tetramethylammonium heptadecafluorononanoate (TMAHFN)/D<inf>2</inf>O system as determined by<sup>2</sup>H and<sup>14</sup>N NMR. Liquid Crystals. 18(1), 51-60
[Journal article]Authored by: Edwards, P.
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Book

Edwards, PJB., & Jameson, GB. (2019). Structure and stability of whey proteins. In Milk Proteins: From Expression to Food. (pp. 251 - 291).
[Chapter]Authored by: Edwards, P., Jameson, G.Edited by: Boland, M.
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Edwards, PJB., & Jameson, GB. (2014). Structure and Stability of Whey Proteins. In Milk Proteins: from Expression to Food, Second Edition. (pp. 201 - 242).
[Chapter]Authored by: Edwards, P., Jameson, G.
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Edwards, PJ., & Jameson, GB. (2014). Structure and stability of whey proteins. In H. singh, M. boland, & A. thompson (Eds.) Milk Proteins: From expression to food. (pp. 201 - 242). : Academic Press
[Chapter]Authored by: Edwards, P., Jameson, G.Edited by: Boland, M.
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Edwards, PB., Creamer, LK., & Jameson, GB. (2008). Structure and Stability of Whey Proteins. In Milk Proteins. (pp. 163 - 203).
[Chapter]Authored by: Edwards, P., Jameson, G.
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Thesis

Matthews, ZM. (2016). The search for biomarkers of facial eczema, following a sporidesmin challenge in dairy cows, using mass spectrometry and nuclear magnetic resonance of serum, urine, and milk. (Doctoral Thesis, Massey University, New Zealand) Matthews, ZM. (2016). The search for biomarkers of facial eczema, following a sporidesmin challenge in dairy cows, using mass spectrometry and nuclear magnetic resonance of serum, urine, and milk. (Doctoral Thesis)
[Doctoral Thesis]Edited by: Edwards, P., Marshall, J.
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Conference

Olivecrona, N., Samuelsson, L., Reis, M., Reis, M., & Edwards, P. (2018). Application of NMR-based Metabolomics to the Investigation of Confinement Odour and Spoilage of Packaged Lamb Meat. Poster session presented at the meeting of ANZMET 2018. Auckland, New Zealand
[Conference Poster]Authored by: Edwards, P.
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Young, T., Alfaro, AC., Lulijwa, R., Walker, S., Samuelsson, L., Edwards, P., . . . Symonds, J. (2018). King Salmon Metabolomics: Establishing the Baseline for Nutrition and Health. Poster session presented at the meeting of ANZMET 2018. Auckland, New Zealand
[Conference Poster]Authored by: Edwards, P.
Matthews, Z., Collett, M., Edwards, P., Marshall, J., Kahnt, A., Fraser, K., . . . Derrick, P. (2018). The search for biomarkers of facial eczema following a sporidesmin challenge in dairy cows. In Proceedings of the 10th International Symposium on Poisonous Plants (ISOPP 10)(pp. 60 - 60). , 10th International Symposium on Poisonous Plants (ISOPP 10)
[Conference Abstract]Authored by: Edwards, P., Marshall, J.
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Sattlegger, E., Harjes, E., Jameson, G., Tu, J., Burr, N., Loo, T., . . . Norris, G. (2018). Deciphering intramolecular interactions in Yih1, a negative regulator of the protein kinase Gcn2.. Poster session presented at the meeting of Translational Control Meeting,Cold Spring Harbor, NY, USA
[Conference Poster]Authored by: Edwards, P., Harjes, S., Jameson, G., Loo, T., Sattlegger, E.
Edwards, PJ., Milan, A., Mitchell, S., Zeng, N., Razman, F., Sharma, P., . . . Shrestha, A. (2017). NMR metabolomics analysis of urine from elderly men fed a high protein diet. Poster session presented at the meeting of Metabolomics 2017: 13th Annual Conference of the Metabolomics Society. Brisbane, Australia
[Conference Poster]Authored by: Edwards, P.
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Carbone, V., Schofield, LR., Nicol, C., Molano, S., Atua, R., Sang, C., . . . Ronimus, RS. (2017). Crystal structure of a UDP-aminosugar 4-epimerase from Methanothermobacter thermautotrophicus. , 14th International Meeting On Thermophiles
[Conference Abstract]Authored by: Edwards, P., Sutherland-Smith, A.
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Edwards, PJ., Samuelsson, L., Olivecrona, N., Reis, M., & Reis, M. (2016). Evaluation of methods for preparation of meat and drip samples for NMR metabolomics. Poster session presented at the meeting of ANZMET 2016 - The Inaugural Australian & New Zealand Metabolomics Conference. Melbourne, Australia
[Conference Poster]Authored by: Edwards, P.
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Harjes, E., Harjes, S., Filichev, V., Jameson, GB., & Edwards, P.(2016, October). How DNA mutating enzymes interact with their DNA substrates. .
[Conference]Authored by: Edwards, P., Filichev, V., Harjes, S., Jameson, G.
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Ronimus, RS., Muetzel, S., Tavendale, MH., Lunn, K., Zhang, Y., Sang, C., . . . Schofield, LR. (2015). Targeting Rument Methanogens to Aid the Development of Methane Mitigation Agents. Poster session presented at the meeting of 23rd International Union for Biochemistry and Molecular Biology (IUBMB) Congress and 44th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology. Foz do Iguaçu, Brazil
[Conference Poster]Authored by: Edwards, P., Sutherland-Smith, A.
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Edwards, PJ., Munro, B., Brox, T., Galvosas, P., Dykstra, R., Harjes, E., . . . Williams, MAK. (2015). The effect of shear-induced reorientation of a bacteriophage nematic phase on the measurement of residual dipolar couplings. Poster session presented at the meeting of ANZMAG Conference. Bay of Islands, New Zealand
[Conference Poster]Authored by: Edwards, P.
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Edwards, PJ., Lunn, K., Denny, WA., Cook, G., Muetzel, S., Whitman, WB., . . . Ronimus, RS. (2014). Investigating transformation and degradation of scaffold compounds in the rumen to advance the development of methanogen-specific inhibitors. Poster session presented at the meeting of III International Conference on Antimicrobial Research - ICAR2014. Madrid, Spain
[Conference Poster]Authored by: Edwards, P.
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Munro, BC., Edwards, PJB., Williams, MAK., & Dykstra, R. (2013). Investigation into new methods for Residual Dipolar Coupling aided structural determination of a small organic molecule. Poster session presented at the meeting of New Zealand Institute of Chemistry Conference. Victoria Univeristy, Wellington, New Zealand
[Conference Poster]Authored by: Edwards, P.
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Kirk, S., Ainscough, EW., Brodie, AM., & Edwards, PJ. (2007). Fluxional behaviour of metal-bearing phosphazenes. Poster session presented at the meeting of Conference of the Inorganic Chemistry Division, Royal Australian Chemical Institute and the Inorganic and Organmetallic Specialist Group, New Zealand Institute of Chemistry. Hobart, TAS
[Conference Poster]Authored by: Edwards, P.
Edwards, PJ. (2006, February). NMR studies of bovine [beta]-lactoglobulin. Presented at Milk Proteins: From Expression to Food. Massey University, Palmerston North, NZ.
[Conference Oral Presentation]Authored by: Edwards, P.
Kirk, S., Ainscough, EW., Brodie, AM., & Edwards, PJ. (2006). Fluxional behaviour of metal-bearing phosphazenes. In Back to the Basics: From Small Molecules to Materials and Surfaces: Proceedings of the New Zealand Institute of Chemistry (NZIC) 2006 Conference(pp. 50 - 52). : New Zealand Institute of Chemistry
[Conference Abstract]Authored by: Edwards, P.
Kirk, S., Ainscough, EW., Brodie, AM., & Edwards, PJ. (2006). Fluxional behaviour of metal-bearing phosphazenes. Poster session presented at the meeting of New Zealand Institute of Chemistry (NZIC) 2006 Conference. Rotorua, NZ
[Conference Poster]Authored by: Edwards, P.
Edwards, PJ., Jameson, GB., Norris, GE., Loo, TS., Ariyaratne, KA., Uhrin, D., . . . Creamer, LK. (2004). Exploring the structure and dynamics of labeled β-lactoglobulin using high field NMR spectroscopy. In Journal of Dairy Science Vol. 87 (pp. 76 - 77). Savoy, IL: American Dairy Science Association
[Conference Abstract]Authored by: Edwards, P., Loo, T.
Edwards, PJ., Jameson, GB., Norris, GE., Loo, TS., Ariyaratne, KA., Uhrin, D., . . . Creamer, LK. (2004, July). Exploring the structure and dynamics of labeled â-lactoglobulin using high field NMR spectroscopy. Presented at ADSA-ASAS-PSA Joint Annual Meeting. St Louis, MO.
[Conference Oral Presentation]Authored by: Edwards, P., Loo, T.
Edwards, PJ., Jameson, GB., Norris, GE., Loo, TS., Creamer, LK., Uhrin, D., . . . Barlow, PN. (2004, February). Backbone dynamics of recombinant bovine â-lactoglobulin A and B monitored by NMR relaxation measurements. Presented at ANZMAG 2004. Barossa Valley, SA.
[Conference Oral Presentation]Authored by: Edwards, P., Loo, T.
Edwards, PJ., Jameson, GB., Norris, GE., Loo, TS., Creamer, LK., Uhrin, D., . . . Barlow, PN. (2004, February). Backbone dynamics of recombinant bovine β-lactoglobulin A and B monitored by NMR relaxation measurements. Presented at 29th Annual Lorne Conference on Protein Structure and Function. Lorne, VIC.
[Conference Oral Presentation]Authored by: Edwards, P., Loo, T.
Hudson, DA., Sciascia, QL., Sanders, R., Norris, GE., Edwards, PJ., Sullivan, P., . . . Farley, PC. (2004, November). The dialysable serum inducer of germ tube formation in Candida albicans. Presented at New Zealand Microbiology Society Annual Conference. Palmerston North, NZ.
[Conference Oral Presentation]Authored by: Edwards, P.
Sawyer, L., Barlow, PN., Boland, M., Creamer, LK., Denton, H., Edwards, PJ., . . . Wu, S. (2002). Milk protein structure: What can it tell the dairy industry?. International Dairy Journal. Vol. 12 (pp. 299 - 310). Essex, UK: Australia-New Zealand Milk Proteins Workshop
[Conference Paper in Published Proceedings]Authored by: Boland, M., Edwards, P., Jameson, G.
Hentschke, R., Edwards, PJB., Boden, N., & Bushby, RJ.A model for isotropic, nematic, and columnar ordering in a self‐assembling system ‐ comparison with the phase behavior of 2,3,6,7,10,11‐hexa‐(1,4,7‐trioxaoctyl)‐triphenylene in water. Macromolecular Symposia. 81 (1)(pp. 361 - 367). 1022-1360.
[Conference]Authored by: Edwards, P.
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BODEN, N., EDWARDS, PJB., & JOLLEY, KW.SELF-ASSEMBLY AND SELF-ORGANIZATION IN MICELLAR LIQUID-CRYSTALS. STRUCTURE AND DYNAMICS OF STRONGLY INTERACTING COLLOIDS AND SUPRAMOLECULAR AGGREGATES IN SOLUTION. (pp. 433 - 461).
[Conference]Authored by: Edwards, P.
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Other

Carbone, V., Ronimus, RS., Muetzel, S., Tavendale, Y., Zhang, C., Dey, D., . . . Ronimus, R. (2015, April). Methanogen Metabolism and How Their Unique Enzymes Can Be Targeted in the Development of Methanogen-Specific Inhibitors. In University of Vicosa, Brazil.
[Oral Presentation]Authored by: Edwards, P., Sutherland-Smith, A.
Jameson, G., Edwards, P., & Penny, E. (2010, May). Origins of life. Presented at Radio New Zealand.
[Oral Presentation]Authored by: Edwards, P.

Teaching and Supervision

Teaching Statement

I teach the Mass Spectrometery and Nuclear Magnetic Resonance (NMR) Spectroscopy content of 123.202 and the NMR component of 123.312.  I also teach a module on Bio-NMR for the 123.711 paper.

Contact Supervisor

Summary of Doctoral Supervision

Position Current Completed
Main Supervisor 0 1
Co-supervisor 1 2

Current Doctoral Supervision

Co-supervisor of:

  • Golnaz Heidari - Doctor of Philosophy
    The search for bio-actives in fermented dairy by products: Metabolomic approaches

Completed Doctoral Supervision

Main Supervisor of:

  • 2016 - Zoe Matthews - Doctor of Philosophy
    The search for biomarkers of facial eczema, following a sporidesmin challenge in dairy cows,using mass spectrometry and nuclear magnetic resonance of serum, urine, and milk

Co-supervisor of:

  • 2021 - Catrina Olivera - Doctor of Philosophy
    Synergistic triple combination antibiotic therapy for Gram-negative bacterial infections
  • 2015 - Christopher Lepper - Doctor of Philosophy
    Effects of High Pressure on DNA and its Components